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Chromosomal mapping of two RBP-J-related genes: Kyo-T and RBP-L
S Tani1, M Taniwaki, Y Taniguchi
1Department of Medical Chemistry, Faculty of Medicine, Kyoto University, Japan.
Journal of Human Genetics
|February 4, 1999
Abstract:
We have recently isolated two genes encoding proteins which have either homology or affinity to RBP-J, a transcription factor involved in Notch signaling. Kyo-T interacts with RBP-J and possibly regulates the function of RBP-J. RBP-L has a highly homologous region with RBP-J but the function of RBP-L is unknown. Fluorescence in situ hybridization analysis of human metaphase chromosomes localized Kyo-T and RBP-L to Xq26 and 20q12-13.1, respectively.