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Paraneoplastic pemphigus: a report of two cases
G F Favia1, L Di Alberti, A Piattelli
1Dental School, University of Bari, Italy.
Oral Oncology
|February 4, 1999
Abstract:
Paraneoplastic pemphigus (PNP) seems to be a separate autoimmune mucocutaneous disease. Forty-five cases have been reported. Almost all cases of PNP are associated with a tumour, mostly with haematologic malignancies. Pemphigus-like autoantibodies are detected by direct and by indirect immunofluorescence studies. These autoantibodies appear to be directed against a novel set of autoantigens. Two cases are presented with clinical, histologic, immunofluorescence and immunoprecipitation findings characteristic of PNP.