Generation of nonimmune islet cells using genetic engineering

Neuronal overexpression of Glo1 or amygdalar microinjection of methylglyoxal is sufficient to regulate anxiety-like behavior in mice.

Behavioural brain research·2015

Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology.

Diabetologia·2011

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress.

Diabetologia·2010

Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes.

Diabetologia·2008

Effect of R-(+)-alpha-lipoic acid on experimental diabetic retinopathy.

Diabetologia·2006

Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide.

Proceedings of the National Academy of Sciences of the United States of America·2005

Transforming growth factor-β1 promotes initiation of entheseal pathological bone formation via osteonectin induction in ankylosing spondylitis.

Journal of molecular medicine (Berlin, Germany)·2026

E-cigarette vaping is associated with pro-fibrotic gene expression in kidney and liver tissues.

Journal of molecular medicine (Berlin, Germany)·2026

Kinase regulation of miRNA networks in cardiometabolic disease: emerging pathways to precision therapy.

Journal of molecular medicine (Berlin, Germany)·2026

Pressure-mediated mechanosensitive Piezo2 channel is activated in neurogenic bladder and promote bladder fibrosis in children.

Journal of molecular medicine (Berlin, Germany)·2026

γδ T cells show distinct responses to CMV after stem cell transplantation.

Journal of molecular medicine (Berlin, Germany)·2026

Tumor-intrinsic TLR4 signaling as a context-dependent rheostat in glioblastoma.

Journal of molecular medicine (Berlin, Germany)·2026

Ligand-dependent interdomain rearrangements drive catalysis by acetyl-CoA synthetases.

Structure (London, England : 1993)·2026

Transannular 1,3-Addition of Cyclic Ethers via C-O Bond Cleavage Triggered by Low-Valent Phosphorus.

Organic letters·2026

Photochemical Reaction Discovery Enabled by the Dynamic Speciation of Copper Complexes.

Angewandte Chemie (International ed. in English)·2026

Regioselective Migratory Ring Expansion of Heterole-Fused Norcaradienes for Modular Access to Azulene-Incorporated Thienoacenes.

Angewandte Chemie (International ed. in English)·2026

Amorphous and highly dispersed NiCoP on anatase TiO2 toward enhanced hydrolytic dehydrogenation of ammonia borane.

Chemical communications (Cambridge, England)·2026

Solid acid catalysts for light naphtha isomerization: reaction mechanism, structure-activity relationships, and future prospects.

Chemical communications (Cambridge, England)·2026

Related Experiment Videos

Generation of nonimmune islet cells using genetic engineering

Related Concept Videos

Neuronal overexpression of Glo1 or amygdalar microinjection of methylglyoxal is sufficient to regulate anxiety-like behavior in mice.

Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology.

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress.

Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes.

Effect of R-(+)-alpha-lipoic acid on experimental diabetic retinopathy.

Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide.

Transforming growth factor-β1 promotes initiation of entheseal pathological bone formation via osteonectin induction in ankylosing spondylitis.

E-cigarette vaping is associated with pro-fibrotic gene expression in kidney and liver tissues.

Kinase regulation of miRNA networks in cardiometabolic disease: emerging pathways to precision therapy.

Pressure-mediated mechanosensitive Piezo2 channel is activated in neurogenic bladder and promote bladder fibrosis in children.

γδ T cells show distinct responses to CMV after stem cell transplantation.

Tumor-intrinsic TLR4 signaling as a context-dependent rheostat in glioblastoma.

Ligand-dependent interdomain rearrangements drive catalysis by acetyl-CoA synthetases.

Transannular 1,3-Addition of Cyclic Ethers via C-O Bond Cleavage Triggered by Low-Valent Phosphorus.

Photochemical Reaction Discovery Enabled by the Dynamic Speciation of Copper Complexes.

Regioselective Migratory Ring Expansion of Heterole-Fused Norcaradienes for Modular Access to Azulene-Incorporated Thienoacenes.

Amorphous and highly dispersed NiCoP on anatase TiO2 toward enhanced hydrolytic dehydrogenation of ammonia borane.

Solid acid catalysts for light naphtha isomerization: reaction mechanism, structure-activity relationships, and future prospects.

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Generation of nonimmune islet cells using genetic engineering

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