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Related Experiment Videos

Silencing chronic cough

R S Irwin1

  • 1University of Massachusetts, Worcester, USA.

Hospital Practice (1995)
|February 5, 1999
PubMed
Summary
This summary is machine-generated.

Most chronic cough cases stem from identifiable causes like postnasal drip syndrome, asthma, or GERD. Multiple factors can contribute, and treatment response aids diagnosis.

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Area of Science:

  • Pulmonology
  • Gastroenterology
  • Allergy and Immunology

Background:

  • Chronic cough is a common presenting symptom in primary care.
  • Identifying the etiology of chronic cough is crucial for effective management.
  • Several conditions are frequently implicated in the pathogenesis of chronic cough.

Observation:

  • Postnasal drip syndrome, asthma, and gastroesophageal reflux disease are the most prevalent causes.
  • ACE inhibitor therapy and pertussis are important considerations in the differential diagnosis.
  • A significant proportion of patients (up to 80%) may have multiple contributing factors to their chronic cough.

Findings:

  • The underlying cause of chronic cough is typically identifiable.
  • Diagnostic confirmation can often be inferred from the patient's response to targeted therapies.

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  • Therapeutic response, while indicative, may manifest over a prolonged period.

    • Implications:

    • Accurate diagnosis of chronic cough etiology leads to improved patient outcomes.
    • Understanding the multifactorial nature of cough is essential for treatment success.
    • Clinicians should consider a broad differential diagnosis and monitor treatment response.