[Surgically-induced angiogenesis as basic principle in treatment ov hypovascularized wounds--the nutritive flap]
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Updated: Oct 25, 2026

08:18
Engineered Vascularized Muscle Flap
Published on: January 11, 2016
K J Walgenbach1, M Voigt, R Horch
1Abteilung Plastische und Handchirurgie, Albert-Ludwigs-Universität Freiburg.
Abstract:
Chronic wounds of the lower extremity as a result of diabetes, arteriosclerosis and microangiopathy are of significant clinical relevance, as they result in immobilization, extended hospitalization and cost-intensive treatment. Via transfer of well-vascularized tissue onto chronic wounds as a free transplanted muscle flap, if necessary connected to a venous bypass, angiogenesis is induced and wound healing improved. This concept leads to nonamputational therapy.
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