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Normal ranges of 24-hour pH-metry established in corrected esophageal atresia
J H Bergmeijer1, J Bouquet, F W Hazebroek
1Department of Pediatric Surgery, Sophia Children's Hospital, University Hospital Rotterdam, The Netherlands.
Insights
This study established normal 24-hour pH-metry values for children post-esophageal atresia repair. These findings indicate that esophageal atresia patients with uncomplicated recovery have typical acid reflux levels comparable to healthy children.
Area of Science:
- Pediatric Gastroenterology
- Surgical Outcomes
- Diagnostic Testing
Background:
- Esophageal atresia repair requires understanding postoperative physiological function.
- Baseline data for 24-hour pH-metry in these patients are not well-established.
Purpose of the Study:
- To determine normative 24-hour pH-metry values in children following esophageal atresia correction.
- To compare these values with those of healthy children.
Main Methods:
- Conducted 24-hour esophageal pH-metry without medication in 13 post-operative esophageal atresia patients.
- Utilized a flexible glass electrode for pH monitoring in a hospital setting.
Main Results:
- The mean reflux index was 4.08%.
- The average total number of reflux periods (pH < 4) was 21.
- The mean number of prolonged reflux periods (pH < 4, > 5 minutes) was 2.5.
Conclusions:
- 24-hour pH-metry values in asymptomatic patients after esophageal atresia repair are similar to those in age-matched healthy children.
- This suggests normal esophageal acid exposure in successfully treated patients.
Background:
This study was undertaken to determine baseline values of 24-hour pH-metry in children who had undergone correction for esophageal atresia.
Methods:
A 24-hour pH-metry without medication was conducted in 13 patients with an uncomplicated postoperative course after correction of esophageal atresia. The pH-metry was performed in the hospital with a flexible glass electrode.
Results:
The mean reflux index was 4.08%, the mean total number of reflux periods with a pH less than 4 was 21, and the mean number of periods of pH less than 4 lasting longer than 5 minutes was 2.5.
Conclusions:
Twenty-four-hour pH-metry values in asymptomatic esophageal atresia patients are the same as in children from the same age group with normal anatomy.