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Related Experiment Videos

Aggressive enterogenous cyst with extensive craniospinal spread: case report

A Perry1, B W Scheithauer, B W Zaias

  • 1Mayo Clinic, Rochester, Minnesota, USA.

Neurosurgery
|February 5, 1999
PubMed
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Widespread craniospinal dissemination of enterogenous cysts, previously considered rare, is reported following incomplete resection. This case highlights the importance of complete surgical removal to prevent extensive recurrence.

Area of Science:

  • Neurology
  • Neurosurgery
  • Pathology

Background:

  • Enterogenous cysts are typically benign, malformative spinal lesions.
  • Recurrences are known, particularly in rare intracranial presentations.
  • Craniospinal dissemination has not been previously documented.

Observation:

  • A 63-year-old woman with a history of cerebellar enterogenous cyst presented with widespread cysts 14 years post-incomplete resection.
  • Histological examination confirmed multiple enterogenous cysts without malignancy.
  • Low proliferative indices (Ki-67 < 1%, one at 4%) and rare p53 overexpression were noted.

Findings:

  • The patient underwent multiple spinal resections for progressive neurological deficits.
  • Craniospinal radiation therapy was administered due to recurrent and progressive disease.

Related Experiment Videos

  • This is the first reported case of extensive craniospinal dissemination of enterogenous cysts.

    • Implications:

    • Incomplete resection of enterogenous cysts can lead to rare but severe craniospinal dissemination.
    • Early and aggressive surgical intervention is crucial for optimal patient outcomes.
    • This case underscores the need for thorough surgical management of enterogenous cysts.