Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biotransformations with peroxidases

W Adam1, M Lazarus, C R Saha-Möller

  • 1Institute of Organic Chemistry, University of Würzburg, Germany. Adam@chemie.uni-wuerzburg.de

Advances in Biochemical Engineering/Biotechnology
|February 6, 1999
PubMed
Summary

Enzymes, as chiral catalysts, enable the synthesis of optically active compounds. This review highlights recent advances in peroxidase-catalyzed reactions for preparing enantiomerically pure molecules, crucial for pharmaceuticals and agrochemicals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Associations between KIR/KIR-ligand genotypes and clinical outcome for patients with advanced solid tumors receiving BEMPEG plus nivolumab combination therapy in the PIVOT-02 trial.

Cancer immunology, immunotherapy : CII·2023
Same author

A multicenter, open-label, expanded phase 2 study to evaluate the safety and efficacy of etirinotecan pegol, a polymer conjugate of irinotecan, in women with recurrent platinum-resistant or refractory ovarian cancer.

Gynecologic oncology·2017
Same author

Dopamine D1 receptor subtype mediates acute stress-induced dendritic growth in excitatory neurons of the medial prefrontal cortex and contributes to suppression of stress susceptibility in mice.

Molecular psychiatry·2017
Same author

5,6-Epoxidation of All-trans-retinoic Acid with Soybean Lipoxygenase-2 and -3.

Bioscience, biotechnology, and biochemistry·2016
Same author

Measurement of J/ψ and ψ(2S) Prompt Double-Differential Cross Sections in pp Collisions at sqrt[s]=7 TeV.

Physical review letters·2015
Same author

Combined Measurement of the Higgs Boson Mass in pp Collisions at sqrt[s]=7 and 8 TeV with the ATLAS and CMS Experiments.

Physical review letters·2015

Area of Science:

  • Biocatalysis
  • Organic Chemistry
  • Green Chemistry

Background:

  • Enzymes are chiral catalysts essential for asymmetric synthesis.
  • Producing enantiomerically pure compounds is vital for pharmaceuticals and agrochemicals.
  • Developing environmentally friendly synthetic processes remains a key challenge.

Purpose of the Study:

  • To review recent advances in peroxidase-catalyzed transformations.
  • To emphasize the preparative applications of these enzymatic reactions.
  • To showcase enzymes as sustainable catalysts for asymmetric synthesis.

Main Methods:

  • Summarizing literature on peroxidase-catalyzed reactions.
  • Focusing on selective oxidations of electron-rich substrates.
  • Highlighting enantioselective synthesis of valuable compounds.

Related Experiment Videos

Main Results:

  • Peroxidases catalyze diverse selective oxidations, including hydroxylation, oxyfunctionalization, epoxidation, and halogenation.
  • Enzymatic reduction of hydroperoxides offers enantioselective pathways.
  • Recent advances demonstrate significant progress in preparative applications.

Conclusions:

  • Enzymes offer an environmentally acceptable approach to synthesizing enantiomerically pure compounds.
  • Peroxidase-catalyzed reactions provide efficient and selective methods for organic synthesis.
  • The review underscores the growing importance and applicability of biocatalysis in industry.