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Anti-HIV coumarins from Calophyllum seed oil
C Spino1, M Dodier, S Sotheeswaran
1Université de Sherbrooke, Département de Chimie, Qc., Canada.
Bioorganic & Medicinal Chemistry Letters
|February 6, 1999
Abstract:
The seeds of Calophyllum cerasiferum Vesque (Family-Clusiaceae), and Calophyllum inophyllum Linn. (Family-Clusiaceae) contain several known coumarins, among which were the potent HIV reverse transcriptase inhibitors costatolide and inophyllum P. Calophyllum cerasiferum contained (-)-calanolide B as its major coumarin constituent in significant amount and thus constitute a renewable source of this compound.