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Organometallic flavonoid derivatives as spectroscopic probes
C E Anson1, C S Creaser, J A Downie
1School of Chemical Sciences, University of East Anglia, Norwich, UK.
Bioorganic & Medicinal Chemistry Letters
|February 6, 1999
Abstract:
Derivatives of naringenin have been synthesized with organometalcarbonyl reporting groups for IR spectroscopy attached at C-2, C-3', or C-6, and the products have been tested for the induction of nod gene expression using a Rhizobium leguminosarum strain which contains the Escherichia coli lacZ (beta-galactosidase) gene fused to nodABC. Derivatives with an OMe substituent within the reporting group moiety showed residual gene induction activity.