Ethacrynic acid--an inhibitor of L-asparagine synthetase

Biosynthetic ganciclovir triphosphate: its isolation and characterization from ganciclovir-treated herpes simplex thymidine kinase-transduced murine cells.

Biochemical and biophysical research communications·2001

Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis.

Current medicinal chemistry·1999

Carbocyclic analogues of the potent cytidine deaminase inhibitor 1-(beta-D-ribofuranosyl)-1,2-dihydropyrimidin-2-one (zebularine).

Journal of medicinal chemistry·1998

Biochemical consequences of resistance to a recently discovered IMP dehydrogenase inhibitor, benzamide riboside, in human myelogenous leukemia K562 cells.

Journal of experimental therapeutics & oncology·1996

Identification of a novel inhibitor (NSC 665564) of dihydroorotate dehydrogenase with a potency equivalent to brequinar.

Biochemical and biophysical research communications·1996

Studies on the mechanism of action of 1-beta-D-arabinofuranosyl-5-azacytosine (fazarabine) in mammalian lymphoblasts.

Journal of experimental therapeutics & oncology·1996

Src inhibition attenuates neuroinflammation via promoting p62 UFMylation-dependent microglial mitophagy.

Biochemical pharmacology·2026

Sephin1 directly targets PHB2 to activate PINK1-PRKN-dependent mitophagy and alleviate α-synuclein neurotoxicity in Parkinson's disease models.

Biochemical pharmacology·2026

Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling.

Biochemical pharmacology·2026

Damage-associated molecular patterns in skeletal muscle: a double-edged sword - from sterile inflammation initiation to precision targeted therapeutic strategies.

Biochemical pharmacology·2026

Melatonin attenuates hyperglycemia-induced platelet dysfunction by preserving redox balance and mitochondrial function.

Biochemical pharmacology·2026

Kuwanon E sensitizes hepatocellular carcinoma cells to disulfidptosis via MTOR-mediated autophagy blockade.

Biochemical pharmacology·2026

Fractional Factorial Design-Guided Optimization of Flavonoid Content and Antioxidant Capacity in Justicia gendarussa Leaf Extracts and UHPLC-HRMS-Based Metabolite Characterization.

Pharmaceuticals (Basel, Switzerland)·2026

Structure-based rational design and biological evaluation of a quinazoline-based EGFR exon 20 insertion inhibitor.

Journal of enzyme inhibition and medicinal chemistry·2026

Characterization of a Novel Camellia fascicularis Mutant and Its Metabolic Regulation of Flavonoid Biosynthesis.

Phytochemistry·2026

Optimization of dsRNA Length and Target Position for Enhanced RNA Interference Efficiency Targeting the Chitinase Gene MsChi2 in Mythimna separata.

Insects·2026

Reconstruction of de novo verazine biosynthesis in Saccharomyces cerevisiae and computational analysis of cholesterol-binding geometry for 22R hydroxylation by VcCYP90B27 to dissect the cyclopamine biosynthetic pathway.

Engineering in life sciences·2026

Structure-guided identification of catalytic determinants in ZmGA20ox enables rational CRISPR target selection for gibberellin engineering in maize.

Frontiers in plant science·2026

Related Experiment Videos

Ethacrynic acid--an inhibitor of L-asparagine synthetase

Related Concept Videos

Biosynthetic ganciclovir triphosphate: its isolation and characterization from ganciclovir-treated herpes simplex thymidine kinase-transduced murine cells.

Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis.

Carbocyclic analogues of the potent cytidine deaminase inhibitor 1-(beta-D-ribofuranosyl)-1,2-dihydropyrimidin-2-one (zebularine).

Biochemical consequences of resistance to a recently discovered IMP dehydrogenase inhibitor, benzamide riboside, in human myelogenous leukemia K562 cells.

Identification of a novel inhibitor (NSC 665564) of dihydroorotate dehydrogenase with a potency equivalent to brequinar.

Studies on the mechanism of action of 1-beta-D-arabinofuranosyl-5-azacytosine (fazarabine) in mammalian lymphoblasts.

Src inhibition attenuates neuroinflammation via promoting p62 UFMylation-dependent microglial mitophagy.

Sephin1 directly targets PHB2 to activate PINK1-PRKN-dependent mitophagy and alleviate α-synuclein neurotoxicity in Parkinson's disease models.

Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling.

Damage-associated molecular patterns in skeletal muscle: a double-edged sword - from sterile inflammation initiation to precision targeted therapeutic strategies.

Melatonin attenuates hyperglycemia-induced platelet dysfunction by preserving redox balance and mitochondrial function.

Kuwanon E sensitizes hepatocellular carcinoma cells to disulfidptosis via MTOR-mediated autophagy blockade.

Fractional Factorial Design-Guided Optimization of Flavonoid Content and Antioxidant Capacity in Justicia gendarussa Leaf Extracts and UHPLC-HRMS-Based Metabolite Characterization.

Structure-based rational design and biological evaluation of a quinazoline-based EGFR exon 20 insertion inhibitor.

Characterization of a Novel Camellia fascicularis Mutant and Its Metabolic Regulation of Flavonoid Biosynthesis.

Optimization of dsRNA Length and Target Position for Enhanced RNA Interference Efficiency Targeting the Chitinase Gene MsChi2 in Mythimna separata.

Reconstruction of de novo verazine biosynthesis in Saccharomyces cerevisiae and computational analysis of cholesterol-binding geometry for 22R hydroxylation by VcCYP90B27 to dissect the cyclopamine biosynthetic pathway.

Structure-guided identification of catalytic determinants in ZmGA20ox enables rational CRISPR target selection for gibberellin engineering in maize.

Related Experiment Videos

Ethacrynic acid--an inhibitor of L-asparagine synthetase

Related Concept Videos

Related Articles