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Elevation of the pacing threshold: a side effect in a patient with pacemaker undergoing therapy with doxorubicin and
1Division of Cardiology, Department of Internal Medicine, Philipps University, Marburg, Germany.
Oncology
|February 9, 1999
Abstract:
A 56-year-old female patient with an IgG plasmocytoma first diagnosed 5 years before underwent 3 cycles of chemotherapy according to the VAD scheme. A VVI pacemaker had been implanted 3 years earlier. After each cycle, the output of the pacemaker had to be increased as the pacing threshold had increased, resulting in a slow pulse. This case demonstrates that patients with a pacemaker that undergo chemotherapy with cardiotoxic agents must be followed carefully.