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Orbital development after enucleation in early childhood
T R Fountain1, S Goldberger, A L Murphree
1Doheny Eye Institute, University of Southern California, Los Angeles, USA.
Ophthalmic Plastic and Reconstructive Surgery
|February 9, 1999
Summary
Orbital implantation after enucleation in children does not impede orbital growth. This study found no significant difference in orbital dimensions, suggesting normal development is maintained.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Medical Imaging
Background:
- Enucleation is a common procedure for retinoblastoma in children.
- Concerns exist regarding potential orbital growth retardation after enucleation and implantation.
- Understanding long-term orbital development is crucial for patient outcomes.
Purpose of the Study:
- To evaluate orbital growth in children following enucleation and orbital implantation for retinoblastoma.
- To determine if enucleation with orbital implants affects orbital dimensions over time.
Main Methods:
- A cohort of children undergoing unilateral enucleation for retinoblastoma was studied.
- Exclusion criteria included prior radiation or chemotherapy.
- Orbital dimensions were measured and compared between the treated and contralateral orbits over a mean follow-up of 8.33 years.
Main Results:
- No statistically significant differences were observed in any measured orbital dimensions.
- Both enucleated and fellow orbits demonstrated comparable linear measurements.
Conclusions:
- Enucleation combined with a large orbital implant does not result in orbital growth retardation in children.
- This suggests that orbital implants can support normal orbital development post-enucleation.