Orbital development after enucleation in early childhood
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Updated: Aug 13, 2026
A Highly Reproducible and Straightforward Method to Perform In Vivo Ocular Enucleation in the Mouse after Eye Opening
Published on: October 6, 2014
T R Fountain1, S Goldberger, A L Murphree
1Doheny Eye Institute, University of Southern California, Los Angeles, USA.
Purpose:
To identify growth retardation in the orbits of children who have undergone enucleation and orbital implantation.
Methods:
Children who underwent unilateral enucleation for retinoblastoma were examined. Any patient who had received external beam radiation or chemotherapy was excluded. Follow-up time was 5.5 to 10 years (mean, 8.33 years). Several linear measurements were made on the enucleated orbit and the fellow orbit. These measurements were compared using the paired Student t test and multivariate analysis of variance.
Results:
There was no statistically significant difference in any of the measured orbital dimensions between the enucleated and fellow orbits.
Conclusions:
Enucleation in children, when combined with a large orbital implant, does not cause orbital growth retardation.
