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[Biological markers of schizophrenic symptoms: functional neuroimaging]
B Crespo-Facorro1, F Manes, C Plebst
1Department of Psychiatry, MHCRC, University of Iowa College of Medicine, USA. bene@kety.psychiatry.uiowa
Actas Luso-Espanolas De Neurologia, Psiquiatria Y Ciencias Afines
|February 9, 1999
Abstract:
Despite heterogeneous phenotype, lack of pathognomonic symptoms and great variability of symptoms during the course of the illness, functional neuroimaging studies have showed specific patterns of activation associated to particular schizophrenic symptoms or symptom dimensions. Negative symptoms have been associated to hypofrontality; auditory hallucinations seem to be related to abnormalities in brain regions involved in language and, reality distortion dimension has been associated to left temporal lobe impairments.