Survival of patients on chronic hemodialysis: single center experience

M Polenakovik1, A Sikole, N Stojcev

  • 1Department of Nephrology, University Clinical Center, Skopje, Republic of Macedonia. maknefpo@nic.mpt.com.mk

Artificial Organs
|February 9, 1999
PubMed

Insights

This hemodialysis study found a 5-year survival rate of 58%, with women and younger patients showing better outcomes. Survival rates varied by kidney disease etiology, with cardiac issues being the leading cause of death.

Area of Science:

  • Nephrology
  • Clinical Medicine
  • Public Health

Background:

  • Hemodialysis (HD) is a critical treatment for end-stage renal disease.
  • Long-term survival data in HD populations are essential for clinical practice and healthcare planning.
  • Understanding factors influencing survival is key to improving patient outcomes.

Purpose of the Study:

  • To analyze patient survival trends over an 11-year period at a chronic intermittent hemodialysis center.
  • To identify demographic, clinical, and etiological factors associated with survival in HD patients.
  • To determine the primary causes of mortality in this patient cohort.

Main Methods:

  • Retrospective analysis of 404 patients undergoing chronic intermittent hemodialysis over 11 years.
  • Data collection included patient demographics, HD treatment details, and survival status.
  • Statistical analysis to correlate survival rates with patient characteristics and causes of death.

Main Results:

  • The overall 5-year survival rate was 58%.
  • Women demonstrated longer survival than men; age was a significant survival predictor.
  • Patients with chronic glomerulonephritis and adult polycystic kidney disease had superior survival, while diabetic and hypertensive nephropathy patients had poorer outcomes.
  • Leading causes of death included cardiac-related issues (44%), cerebrovascular accidents (15%), and sepsis (11%).

Conclusions:

  • Survival in hemodialysis patients is influenced by gender, age, and underlying kidney disease etiology.
  • Cardiac disease remains a major cause of mortality in the hemodialysis population.
  • Continuous monitoring and targeted interventions are necessary to improve long-term outcomes for hemodialysis patients.

Related Concept Videos

Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...