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Headache in hypothyroidism. Prevalence and outcome under thyroid hormone therapy
T Moreau1, E Manceau, F Giroud-Baleydier
1Service of Neurology, University Hospital, Dijon, France.
Objective:
To evaluate the frequency of headache in patients with hypothyroidism.
Design:
A prospective study of a cohort of patients with hypothyroidism.
Setting:
Outpatients or inpatients in a headache clinic and endocrinological clinic.
Patients:
102 adults, ages 35 to 78 (83F, 19M) experiencing clinical and biological hypothyroidism.
Results:
Thirty-one patients with hypothyroidism of 102 (30%) presented with headache 1 to 2 months after the first symptoms of hypothyroidism. The headache was slight, nonpulsatile, continuous, bilateral, and salicylate responsive and disappeared with thyroid hormone therapy.
Conclusion:
The authors believe there is a prevalence of nonspecific headache in hypothyroidism and that it has a particular response to thyroid hormone therapy. Hypothyroidism is another cephalalgia with an endocrinological cause after menstrual cephalalgia. We suspect a metabolic or vascular pathophysiological process.