Metabolic unit of pulp-dentinal complex of human tooth

The change of dentin depends on odontoblast's metabolism (synthesis and secretion), and the result of those cells activity is apposition of dentin: physiological or reactive. Odontoblasts, dentinal tubuli with odontoblastic processus and peritubular zone, they all make metabolic unit of dentin, and they are the major part of circumpulpal dentin structure. Functional activities of the tooth are the base for constant changes during the entire life of circumpulpal dentin. The apposition, and also the resorption of dentinal tissue, can be found as the respond to trauma, pathological conditions, or after the therapeutic interventions.