Trichophyton mentagrophytes infection in laboratory white mice
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Abstract:
Trichophyton mentagrophytes infection was studied in a breeding colony of 42 white mice. Symptoms were observed in only 3 out of the 12 animals shown to carry dermatophyte on their coats. Literature on Trichophyton mentagrophytes infection mice is reviewed. The use of the technique developed by Mariat & Tapia (16) to isolate dermatophytes on cultures, specially for epidemiological surveys, is postulated. Attention is called to the importance of healthy animals, directly or indirectly, as carriers of fungi and sources of infection to other animals and human beings.
Insights
Dermatophyte fungi, specifically Trichophyton mentagrophytes, can infect mice. Even asymptomatic carriers pose a risk, highlighting the importance of healthy animals in preventing fungal spread to other animals and humans.
Area of Science:
- Veterinary Mycology
- Dermatophytosis Research
- Animal Epidemiology
Background:
- Trichophyton mentagrophytes is a common cause of fungal infections.
- Mice are susceptible to dermatophyte infections.
- Understanding carrier states is crucial for disease control.
Purpose of the Study:
- To investigate Trichophyton mentagrophytes infection in a mouse breeding colony.
- To assess the prevalence of asymptomatic carriers.
- To review existing literature on mouse dermatophytosis.
Main Methods:
- Studied a colony of 42 white mice.
- Observed clinical symptoms.
- Identified dermatophyte carriers on coats.
- Reviewed relevant scientific literature.
Main Results:
- Symptoms were observed in only 3 of 12 infected mice.
- A significant proportion of infected mice were asymptomatic carriers.
- The Mariat & Tapia technique is suitable for epidemiological surveys.
Conclusions:
- Asymptomatic mice can carry and transmit Trichophyton mentagrophytes.
- Healthy animals are vital for preventing fungal transmission.
- Epidemiological surveys are important for controlling dermatophyte spread.