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Related Experiment Videos

Pseudoaccommodation: BioComFold versus a foldable silicone intraocular lens

J M Legeais1, L Werner, L Werner

  • 1Department of Ophthalmology, Hôtel-Dieu Hospital, Paris, France.

Journal of Cataract and Refractive Surgery
|February 10, 1999
PubMed
Summary

The BioComFold intraocular lens (IOL) demonstrated greater forward optic shifts during accommodation but did not significantly increase pseudoaccommodation amplitude compared to control IOLs.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Cataract surgery often involves intraocular lens (IOL) implantation to restore vision.
  • Achieving functional pseudoaccommodation is a key goal in IOL design to improve uncorrected visual acuity at multiple distances.
  • The BioComFold IOL features a novel design intended to enhance pseudoaccommodation through forward optic movement.

Purpose of the Study:

  • To evaluate the correlation between anteroposterior axis shifts of the BioComFold foldable intraocular lens (IOL) and the resulting pseudoaccommodation amplitude.
  • To compare the pseudoaccommodation amplitude and IOL movement between the BioComFold IOL and a standard foldable control IOL.

Main Methods:

  • A prospective study involving 30 patients undergoing cataract surgery with either BioComFold or control IOL implantation.

Related Experiment Videos

  • Pseudoaccommodation amplitude was measured by subjective refractive blur with best distance correction.
  • Anterior chamber depth and pupil diameter were objectively measured before and after cycloplegic and miotic drops.

    • Main Results:

    • The BioComFold IOL group exhibited significantly greater forward optic shifts along the anteroposterior axis during accommodation compared to the control group (P = .0215).
    • No statistically significant difference in pseudoaccommodation amplitude was observed between the BioComFold and control IOL groups (P = .6737).
    • Pupil diameter also showed no significant difference between the two groups (P = .4014).

    Conclusions:

    • The BioComFold IOL design successfully induces greater anterior optic displacement during the accommodative effort.
    • Despite the increased optic mobility, this forward shift did not translate into a statistically significant improvement in pseudoaccommodation amplitude.
    • Further research may be needed to optimize IOL designs for enhanced functional pseudoaccommodation.