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Anticardiolipin antibody in recurrent spontaneous aborting and fertile women
E Couto1, R Barini, J L Pinto e Silva
1Department of Tocogynecology, Universidade Estadual de Campinas (UNICAMP)-Campinas, Brazil.
Objective:
To determine the association between the presence of anticardiolipin antibody and a history of recurrent spontaneous abortion.
Study Design:
Clinical controlled study.
Location:
Department of Gynecology and Obstetrics-University of Campinas (UNICAMP).
Subjects:
52 individuals with recurrent spontaneous abortion were included in Group 1 and 104 individuals with at least one live born child in Group 2. Elapsed time from last delivery to blood sampling varied from six months to two years.
Method:
Between November 1993 and November 1994, patients' blood samples were screened for anticardiolipin antibody by ELISA, as described by Triplett, Barna and Unger (1993).
Analysis:
Chi-square and Fisher's Exact tests were used for statistical analysis. Student's "t" test was used to compare the means.
Results:
There was no statistical difference in the presence of the anticardiolipin antibody between Group 1 (zero and 2.9%) and Group 2 (7.7 and 5.8%).
Conclusion:
There was no association between the presence of anticardiolipin antibody and recurrent spontaneous abortion.