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Visceral intestinal Buerger's disease

J T Lie1

  • 1Department of Pathology, University of California, Davis, School of Medicine, and University of California Davis Medical Center, Sacramento 95817, USA.

International Journal of Cardiology
|February 10, 1999
PubMed
Summary

Buerger's disease, a rare inflammatory condition, typically affects young men. This study highlights two women with intestinal Buerger's disease, a previously undocumented occurrence, who succumbed to ischemic bowel complications.

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Area of Science:

  • Vascular Medicine
  • Gastroenterology
  • Pathology

Background:

  • Buerger's disease is an inflammatory vaso-occlusive condition primarily affecting young male tobacco users.
  • It commonly impacts limb arteries and veins, with rare instances of visceral involvement.
  • Previously, only 16 cases of intestinal Buerger's disease were reported, all in men.

Purpose of the Study:

  • To report the first documented cases of intestinal Buerger's disease in young women.
  • To underscore the potential for severe, fatal outcomes from ischemic bowel complications in this rare presentation.

Main Methods:

  • Case report of two female patients diagnosed with intestinal Buerger's disease.
  • Review of clinical presentation, pathological findings, and outcomes.

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  • Literature review of previously reported visceral Buerger's disease cases.

    • Main Results:

    • The two female patients presented with symptoms of ischemic bowel disease.
    • Both patients experienced fatal complications related to intestinal ischemia.
    • This expands the known demographic of intestinal Buerger's disease to include women.

    Conclusions:

    • Intestinal Buerger's disease can occur in women, challenging previous observations.
    • This condition can lead to severe ischemic bowel complications and mortality.
    • Further research is needed to understand the etiology and full spectrum of Buerger's disease.