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Published on: February 3, 2012
Myasthenia gravis: another autoimmune disease associated with hepatitis C virus infection
1Department of Internal Medicine, University Hospital Gasthuisberg, Leuven, Belgium.
Abstract:
We report on a male Egyptian patient who developed myasthenia gravis with typical symptoms, beneficial response to pyridostigmine, and the presence of anti-acetylcholine receptor antibodies and anti-striated muscle antibodies during the course of a chronic hepatitis C infection complicated by liver cirrhosis. As also reported for the herpes simplex and for the HIV virus, hepatitis C may lead to myasthenia gravis via a mechanism of cross-reactivity between viral epitopes and the acetylcholine receptor.
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