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[Acute consumption coagulopathies. 120 cases]

A Larcan, H Lambert, M C Laprevote-Heully

    La Nouvelle Presse Medicale
    |December 4, 1976
    PubMed
    Summary
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    Consumption coagulopathy, a critical condition, often arises from pregnancy complications or severe stress. Early diagnosis and etiological treatment, including heparin therapy, are vital for managing shock and hemorrhagic syndromes.

    Area of Science:

    • Critical Care Medicine
    • Hematology

    Background:

    • Consumption coagulopathy is a frequent complication in resuscitation departments.
    • It is intricately linked with underlying stress and can exacerbate visceral lesions.

    Purpose of the Study:

    • To review 120 cases of consumption coagulopathy.
    • To analyze etiologies, clinical manifestations, and treatment outcomes.

    Main Methods:

    • Retrospective review of 120 cases with diverse etiologies.
    • Analysis of clinical data, biological evolution, and therapeutic interventions.

    Main Results:

    • Pregnancy complications (61 cases) and infections (23 cases) were common etiologies.
    • Shock (76%) and hemorrhagic syndrome (73%) were prevalent.

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  • Visceral complications (renal, hepatic, respiratory, neurological, digestive) frequently developed.

    • Conclusions:

    • Diagnosis requires integrated clinical and biological assessment.
    • Etiological and pathophysiological treatment is crucial.
    • Controlled heparin therapy was systematically administered in this series.