Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Visual evoked potentials in multiple sclerosis]

J Paty, P Brenot, P Henry

    Revue Neurologique
    |September 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Combined multimodal therapy in high-risk patients with chronic thromboembolic pulmonary hypertension and both distal and proximal lesions: A prospective observational cohort study.

    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2025
    Same author

    [How I deal with this unusual paravalvular leak].

    Annales de cardiologie et d'angeiologie·2024
    Same author

    Sinus Venosus ASDs: Imaging and Percutaneous Closure.

    Current cardiology reports·2021
    Same author

    [Thoracic pain of unusual cause].

    La Revue de medecine interne·2021
    Same author

    [Training simulation during the announcement of fetal malformation discovered on screening ultrasound: Results of a pilot study].

    Gynecologie, obstetrique, fertilite & senologie·2020
    Same author

    [Para valvular leak closure in TAVI].

    Annales de cardiologie et d'angeiologie·2019
    Same journal

    Geographic disparities in MRI features of ischemic stroke and small vessel disease: A comparative study between French Guiana and mainland France. Findings from the BECATOUR multicenter registry.

    Revue neurologique·2026
    Same journal

    Continuous subcutaneous perfusion of apomorphine in Parkinson's disease: Towards monotherapy?

    Revue neurologique·2026
    Same journal

    Neuro-Whipple presenting as autoimmune encephalitis.

    Revue neurologique·2026
    Same journal

    Multimodal assessment of minimally conscious state and cognitive motor dissociation in neurocritical care: A critical review.

    Revue neurologique·2026
    Same journal

    Development of a new episodic memory assessment tool (NEM): Preliminary data and clinical perspectives.

    Revue neurologique·2026
    Same journal

    Novel variants and rare clinical presentations in MFN2-related Charcot-Marie-Tooth disease: Insights from 10 families.

    Revue neurologique·2026
    See all related articles

    Multiple sclerosis patients show significant visual evoked potential abnormalities, primarily delayed retino-cortical conduction. This electrophysiological method aids in diagnosing multiple sclerosis and understanding its neurological impact.

    Area of Science:

    • Neuroscience
    • Ophthalmology
    • Clinical Electrophysiology

    Context:

    • Multiple sclerosis (MS) diagnosis relies on clinical criteria and neurological assessments.
    • Electrophysiological methods offer objective measures of neural pathway function.
    • Visual evoked potentials (VEPs) assess the integrity of the visual pathway from retina to cortex.

    Purpose:

    • To investigate the diagnostic utility of dynamic electroretinoencephalography (VER) in patients with definite multiple sclerosis.
    • To compare VEP abnormalities in MS patients with those in optic neuritis and healthy controls.
    • To correlate VEP findings with clinical parameters of MS, such as optic neuritis and disease activity.

    Summary:

    • A study of 32 MS patients revealed abnormalities in 77% of VEP tests, predominantly delayed latency indicating slowed retino-cortical conduction.

    Related Experiment Videos

  • VEP abnormalities were significantly more frequent in MS (77%) than in optic neuritis (35%), suggesting higher specificity for MS.
  • Electrophysiological findings were analyzed against clinical presentation, including subclinical optic neuritis, disease duration, and activity, highlighting links to demyelination.

    • Impact:

    • Dynamic electroretinoencephalography demonstrates potential as a specific and sensitive electrophysiological tool for diagnosing multiple sclerosis.
    • Findings underscore the role of VEPs in detecting subclinical visual pathway involvement in MS.
    • This research contributes to understanding the relationship between demyelination and nervous conduction deficits in multiple sclerosis.