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Related Experiment Videos

[Chorea minor under ovulation inhibitors]

P Jutz, P Clavadetscher, E Ketz

    Schweizerische Medizinische Wochenschrift
    |June 5, 1976
    PubMed
    Summary
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    Oral contraceptives can trigger hyperkinesis in women with a history of rheumatic carditis and chorea minor. Discontinuation leads to remission, suggesting oral contraceptives are contraindicated for these patients.

    Area of Science:

    • Neurology
    • Cardiology
    • Pharmacology

    Context:

    • A 26-year-old woman with a history of rheumatic carditis and chorea minor experienced hyperkinesis.
    • The hyperkinesis recurred three weeks after initiating oral contraception.

    Purpose:

    • To investigate the potential link between oral contraceptive use and hyperkinesis in a patient with a history of rheumatic carditis and chorea minor.
    • To highlight the contraindication of oral contraceptives in women with a history of rheumatic fever and chorea.

    Summary:

    • The patient's hyperkinesis resolved rapidly upon withdrawal of oral contraceptives.
    • This suggests a causal relationship between oral contraceptive use and the recurrence of hyperkinesis.
    • The case presents an analogy to chorea gravidarum, occurring in a non-pregnant individual.
    Keywords:
    BiologyCase StudiesCentral Nervous SystemCentral Nervous System EffectsChoreaContraceptionContraceptive Agents, Estrogen--side effectsContraceptive Agents, Female--side effectsContraceptive Agents, Progestin--side effectsContraceptive Agents--side effectsDiseasesEthynodiol Diacetate--side effectsFamily PlanningMestranol--side effectsOral ContraceptivesOral Contraceptives, CombinedPhysiologyResearch MethodologySigns And SymptomsStudies

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    Impact:

    • Oral contraceptives may induce hyperkinesis in susceptible individuals.
    • Clinicians should inquire about oral contraceptive use in young women presenting with chorea minor.
    • A history of rheumatic fever with or without chorea is a contraindication for oral contraceptive prescription.