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[Esophageal function after fundoplication (Nissen)]

G J Krejs, H Bühler, A Akovbiantz

    Schweizerische Medizinische Wochenschrift
    |June 12, 1976
    PubMed
    Summary
    This summary is machine-generated.

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    [Surgical and medical therapy for gastroesophageal reflux disease. Consensus of pro/contra clinical debate].

    Zeitschrift fur Gastroenterologie·2003

    Fundoplication surgery effectively treats gastro-esophageal reflux in most patients. Surgical success is not linked to lower esophageal sphincter pressure or position, indicating other factors are key.

    Area of Science:

    • Gastroenterology
    • Surgical Research
    • Esophageal Physiology

    Context:

    • Gastro-esophageal reflux (GER) is a common condition often treated with surgical intervention.
    • Fundoplication is a surgical procedure to treat GER by reinforcing the lower esophageal sphincter.
    • Evaluating surgical outcomes requires objective physiological and symptomatic assessments.

    Purpose:

    • To investigate the physiological changes and symptom resolution after fundoplication in patients with gastro-esophageal reflux.
    • To determine the correlation between lower esophageal sphincter (LES) function and the success of fundoplication surgery.
    • To assess the impact of hiatus hernia presence on surgical outcomes.

    Summary:

    • Fifteen patients with gastro-esophageal reflux underwent fundoplication, with 13 experiencing significant symptom relief.

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  • Post-operative reflux provocation tests improved, yet resting lower esophageal sphincter pressure did not increase in successfully operated patients.
  • Esophageal function tests were similar in patients with and without post-operative hiatus hernia, suggesting LES pressure and position are not critical for surgical success.

    • Impact:

    • This study suggests that the success of fundoplication for GERD is independent of resting LES pressure and its anatomical position.
    • Findings may guide surgical decision-making and patient expectations regarding GERD treatment outcomes.
    • Highlights the need for further research into the mechanisms underlying successful fundoplication beyond LES pressure augmentation.