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Circulating interleukin-16 in systemic lupus erythematosus

S Lee1, H Kaneko, I Sekigawa

  • 1Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Japan.

British Journal of Rheumatology
|February 11, 1999
PubMed
Abstract

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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