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Moderierende Variablen der Placebowirkung

Strauss-Blasche, Klammer, Marktl

    Forschende Komplementarmedizin
    |February 12, 1999
    PubMed
    Summary

    Psychological factors like doctor

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    Area of Science:

    • Psychology
    • Medical Psychology
    • Behavioral Medicine

    Background:

    • The placebo effect, a well-documented phenomenon in medicine, significantly influences treatment outcomes.
    • Understanding the psychological variables that modulate this effect is crucial for optimizing therapeutic strategies.

    Purpose of the Study:

    • To identify and analyze psychological variables that modify the placebo effect.
    • To explore the expectancy model in relation to placebo response.

    Main Methods:

    • Review of experimental and clinical studies investigating the placebo effect.
    • Analysis based on the expectancy induction and expectancy effect model.

    Main Results:

    • Expectancy strength, prescriber's attitude, patient motivation, perceived importance of change, and freedom of choice positively influence the placebo effect.
    • High self-awareness and prior experience with a treatment method tend to inhibit the placebo effect.
    • Generalized anxiety and hypnotic susceptibility do not appear to significantly modify the placebo effect.

    Conclusions:

    • The placebo effect is significantly modulated by a range of psychological and contextual factors beyond mere expectation.
    • Interventions aimed at enhancing placebo responses should consider prescriber-patient dynamics, patient motivation, and perceived autonomy.
    • Further research into the inhibitory factors like self-awareness could refine placebo-controlled trial designs and clinical applications.

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