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Percutaneous microwave coagulation therapy for hepatocellular carcinoma
T Asahara1, H Nakahara, T Fukuda
1Department of Surgery II, Hiroshima University School of Medicine, Japan.
Hiroshima Journal of Medical Sciences
|February 12, 1999
Summary
Percutaneous microwave coagulation therapy (PMCT) is effective for small hepatocellular carcinoma (HCC) tumors (≤3 cm). Larger or multiple HCC tumors may require alternative treatments like hepatectomy for better outcomes.
Area of Science:
- Hepatobiliary Surgery
- Interventional Radiology
- Oncology
Background:
- Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide.
- Treatment options for HCC include surgical resection, liver transplantation, and locoregional therapies.
- Percutaneous microwave coagulation therapy (PMCT) is an ablative technique used for liver tumors.
Purpose of the Study:
- To compare the efficacy of PMCT with hepatectomy for treating HCC.
- To determine the optimal patient and tumor characteristics for PMCT in HCC management.
Main Methods:
- A comparative study involving 19 patients with HCC.
- Evaluation of PMCT versus hepatectomy.
- Assessment of outcomes based on tumor size and number.
Main Results:
- PMCT showed comparable survival and cancer-free rates to hepatectomy for single HCC tumors ≤3 cm.
- Inadequate coagulation was observed in 6 patients with tumors >3 cm after single-session PMCT.
- Recurrence within 1 year was noted in patients with multiple HCC tumors.
Conclusions:
- PMCT is a viable option for initial treatment of single HCC tumors up to 3 cm in diameter.
- Hepatectomy is recommended for HCC tumors larger than 3 cm.
- PMCT may be less effective for multiple HCC tumors, necessitating further investigation.