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Brachytherapy in early prostate cancer--early experience
B O Jose1, J L Bailen, F H Albrink
1Department of Radiation Oncology, James Graham Brown Cancer Center, USA.
The Journal of the Kentucky Medical Association
|February 12, 1999
Summary
This study reports on 150 early-stage prostate cancer patients treated with radioactive seed implantation (Iodine-125 or Palladium-103). The findings detail the treatment planning and techniques used, based on Seattle guidelines.
Area of Science:
- Oncology
- Radiotherapy
- Urology
Background:
- Brachytherapy with radioactive seeds is a common treatment for early prostate cancer in the US.
- Previous experience has been reported from Seattle treatment centers over the past decade.
Purpose of the Study:
- To report the early experience of 150 radioactive seed implantations for early-stage prostate cancer.
- To describe the treatment planning and current techniques used, based on Seattle guidelines.
Main Methods:
- Utilized Iodine-125 or Palladium-103 radioactive seeds for implantation.
- Involved pre-treatment planning including prostate ultrasound for volume study and CT scan of the pelvis for pubic arch study.
- Employed treatment planning computers for precise dosimetry.
Main Results:
- Treated 150 patients with early-stage prostate cancer.
- Average patient age was 66 years, with a median Gleason score of 5.4 and median PSA of 6.
- Detailed the evolution of prostate cancer treatment and preparation for seed implantation.
Conclusions:
- The study presents initial findings from a series of radioactive seed implantations for early prostate cancer.
- The described methods align with established Seattle guidelines for treatment planning and execution.
- A follow-up report with longer-term results is planned.