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[Vesico-ureteral reflux in pediatrics]
V Fanos1, B J Khoory, S Vecchini
1Clinica Pediatrica, Università degli Studi, Verona.
Minerva Pediatrica
|February 12, 1999
Summary
Vesico-ureteral reflux (VUR) affects 1-2% of children and can lead to kidney damage. Early diagnosis and management, including family support, are crucial for optimal outcomes in pediatric VUR.
Area of Science:
- Pediatric Urology
- Nephrology
- Genetics
Context:
- Vesico-ureteral reflux (VUR) is the most common uropathy in children, affecting 1-2%.
- Neonatal VUR may be a distinct clinical entity.
- Pathogenesis involves genetic, familial, racial, gender, and age factors.
Purpose:
- To review the pathogenesis, diagnosis, renal damage factors, and treatment of VUR.
- To discuss the relationship between VUR and urinary tract infections (UTI).
- To highlight the need for family support in VUR management.
Summary:
- VUR can cause renal damage through direct reflux, UTIs, inflammation, and dysplasia.
- Current diagnostic methods include micturition cystourethrography and nuclear cystography; ultrasound is non-specific.
- New functional and morphological studies are being investigated.
- Treatment strategies for VUR remain debated, with guidelines suggested.
- The strong association between VUR and UTI is emphasized.
Impact:
- Informs clinical practice regarding VUR diagnosis and management in children.
- Highlights the importance of early detection to prevent renal damage.
- Underscores the need for comprehensive patient and family support.
- Guides future research into VUR pathogenesis and treatment.