[Non-specific immunologic reactivity among patients with primary multiple malignant neoplasms]

Under examination were seventy four patients with different combinations of primary multiple malignant tumors. In patients with 2 skin tumor nodes a high percent of delayed allergic reactions was found in response to the use of 2,4-dinitrochlorobenzene (DNCB) and a correlated with the former high coefficient of the percutaneous test with tripan blue (QD). The mentioned indices are diminished as the third or more skin tumor nodes appear. In polyneoplasia involving internal organs delayed allergic reactions were found to be absent and QD markedly reduced.