[Blast-transformation reaction in patients with bone tumors]

The authors have studied phytohemagglutinin stimulation of DNA synthesis in leucocytes cultures of the peripheral blood in patients with some malignant osteoplasms and benign tumors, and the influence of plasma factors on this process, as well. In most cases, lymphocytes of patients with malignant tumors were shown to have a considerably decreased, as compared with the control, level of blasttransformation. No such difference was found for leucocytes cultures of patients with benign tumors.