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Intrarenal reflux

P Uldall, O Frøokjaer, K Kaas Ibsen

    Acta Paediatrica Scandinavica
    |November 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Intrarenal reflux, or pyelotubular backflow, was detected in 9.2% of children with vesico-ureteric reflux. This finding is a definite indication for surgical intervention in pediatric patients.

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    Area of Science:

    • Pediatric Urology
    • Radiology
    • Nephrology

    Background:

    • Vesico-ureteric reflux (VUR) is a common condition in children.
    • Intrarenal reflux (IR) is a less understood complication of VUR.
    • The relationship between IR and renal damage requires further investigation.

    Purpose of the Study:

    • To determine the incidence of intrarenal reflux in children with VUR.
    • To assess the correlation between intrarenal reflux and renal damage.
    • To evaluate the clinical significance of intrarenal reflux in guiding treatment decisions.

    Main Methods:

    • Retrospective review of 76 children with 123 ureters affected by VUR.
    • Micturating cystourethrography (MCU) to detect intrarenal reflux.
    • Excretion urography (EU) to assess renal morphology and damage.

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    Main Results:

    • Intrarenal reflux was identified in 7 patients (9.2%) during MCU.
    • Renal damage was observed in 6% of kidneys with VUR and IR.
    • A direct correlation between IR location and renal damage was noted in some cases.

    Conclusions:

    • Intrarenal reflux is a significant finding in children with VUR.
    • The presence of intrarenal reflux is a strong indicator for surgical intervention.
    • Further research is needed to fully elucidate the pathogenesis of IR and its long-term sequelae.