[Weight increase following administration of insulin to rats with reduced feed intake]

Young male Wistar rats, adapted to single daily administration of feed (from 8.00 to 10.00 a.m.) were studied for the intake of feed, weight gains, and feed consumption per weight gain unit after administration of Superdep insulin in the dose of 10 u kg-1 of body weight. The time limitation of access to food reduced the over-all intake of feed and weight gains and adversely affected the utilization of feed, expressed as consumption per 1 g of weight gain. The administration of insulin partly compensated the adverse effect of the reduced feed intake; this was manifested by better utilization of feeds by the experimental group, in comparison with the control animals.