Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer02:18

Cancer

53.2K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
53.2K
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

1.4K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.4K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

9.6K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
9.6K
Cancer Prevention02:59

Cancer Prevention

7.5K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
7.5K
What is Cancer?02:12

What is Cancer?

13.7K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
13.7K
Cancer Survival Analysis01:21

Cancer Survival Analysis

572
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
572

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hypoxic hepatitis with marked elevation of serum ferritin probably due to activation of intrahepatic macrophages: another form of hypoxic hepatitis hitherto not reported?

Acta gastro-enterologica Belgica·2021
Same author

Successful treatment of duodenal carcinoid tumor by laparoscopy-assisted endoscopic full-thickness resection with lymphadenectomy.

Asian journal of endoscopic surgery·2012
Same author

[Subscapular elastofibroma].

Kyobu geka. The Japanese journal of thoracic surgery·2011
Same author

Reperfusion therapy for acute vertebrobasilar occlusion.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2010
Same author

Reversibility of ischemia evaluated by ischemic duration and residual cerebral blood flow.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2010
Same author

Early recurrence after surgical resection in patients with pathological stage I non-small cell lung cancer.

The Thoracic and cardiovascular surgeon·2009
Same journal

[A Case of Pulmonary Epithelioid Hemangioendothelioma Associated with Multiple Cancers].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same journal

[Long-Term Survival in Three Cases with Pulmonary Metastases from Colorectal Cancer Given Low-Dose S-1 Under a Regimen Combining a Carbohydrate-Restricted Ketogenic Diet, Metformin, Vitamin D, Eicosapentaenoic Acid, and Other Complementary Therapies].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same journal

[Preventive Effect of Saline Eye Wash for Eye Symptoms Due to High-Dose and Intermediate-Dose Cytarabine Therapy].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same journal

[Examination of Factors Affecting the Efficacy of Naldemedine Tosilate Tablets for Opioid-Induced Constipation].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same journal

[Recent Advances in the Treatment of HER2-Altered Solid Tumors].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same journal

[BRAF-Mutant Solid Tumor].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
See all related articles

Related Experiment Video

Updated: Dec 17, 2025

A Minimally Invasive Method for Generating a Syngeneic Orthotopic Mouse Model of Lung Cancer
07:46

A Minimally Invasive Method for Generating a Syngeneic Orthotopic Mouse Model of Lung Cancer

Published on: August 19, 2025

739

[Lung cancer]

T Goya1, R Kawaji, Y Kobayashi

  • 1Dept. of Surgery II, Kyorin University School of Medicine, Tokyo, Japan.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|February 13, 1999
PubMed
Summary
This summary is machine-generated.

Lung cancer survival rates in Japan are low. Clinical staging (c-TNM) and neoadjuvant therapy are crucial for treatment decisions, emphasizing medical oncology

More Related Videos

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
04:04

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

10.8K
Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 19, 2016

24.8K

Related Experiment Videos

Last Updated: Dec 17, 2025

A Minimally Invasive Method for Generating a Syngeneic Orthotopic Mouse Model of Lung Cancer
07:46

A Minimally Invasive Method for Generating a Syngeneic Orthotopic Mouse Model of Lung Cancer

Published on: August 19, 2025

739
Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
04:04

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

10.8K
Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 19, 2016

24.8K

Area of Science:

  • Oncology
  • Thoracic Surgery
  • Medical Research

Context:

  • Lung cancer presents a significant health challenge in Japan, with a low 5-year survival rate of only 10%.
  • Accurate staging is critical for effective lung cancer treatment planning.
  • Neoadjuvant therapy holds a pivotal role in multimodal lung cancer treatment strategies.

Purpose:

  • To highlight the importance of clinical TNM (c-TNM) staging over pathological TNM (p-TNM) in guiding lung cancer treatment.
  • To underscore the critical role of neoadjuvant therapy in lung cancer management.
  • To advocate for clinical trial designs incorporating "intent to treat" principles and emphasizing medical oncology's contribution.

Summary:

  • The clinical TNM (c-TNM) staging system is deemed more critical than the pathological TNM (p-TNM) system for determining lung cancer treatment modalities.
  • Neoadjuvant therapy is positioned as a more significant component in lung cancer treatment compared to other solid tumors.
  • Future clinical research should adopt an "intent to treat" approach, recognizing the expanding role of medical oncology.

Impact:

  • This research emphasizes a shift towards prioritizing clinical staging and neoadjuvant strategies in lung cancer care.
  • It calls for enhanced integration of medical oncology within multidisciplinary treatment teams for lung cancer patients.
  • The findings support the development of robust clinical protocols to improve patient outcomes and survival rates.