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Intracranial leiomyosarcoma in a patient with AIDS
H G Brown1, P C Burger, A Olivi
1Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
Neuroradiology
|February 13, 1999
Abstract:
We report an intracranial leiomyosarcoma in the pontine cistern of a 34-year-old woman infected with the human immunodeficiency virus (HIV). The clinical, radiological and pathological data are reviewed. The tumor was Epstein-Barr virus (EBV) positive by in situ hybridization. This case emphasizes that smooth muscle neoplasms arising in the setting of immunocompromise can occur intracranially, and corroborates a hypothesis that EBV coinfection may have a role in development of these tumors.