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Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
Published on: January 8, 2013
Improved estimation of pericardial potentials from body-surface maps using individualized torso models
R M Arthur1, D G Beetner, H D Ambos
1Department of Electrical Engineering, School of Engineering, Washington University in St. Louis, Missouri 63130, USA.
Journal of Electrocardiology
|February 13, 1999
Summary
Accurate pericardial potential estimation requires individualized torso models. Generic models significantly increase errors in body-surface electrocardiogram (ECG) calculations, limiting clinical use.
Area of Science:
- Biomedical Engineering
- Computational Electrophysiology
- Medical Imaging
Background:
- Clinical inference of pericardial potentials from surface ECGs is hindered by noise and model inaccuracies.
- Torso model errors, including electrode location and geometric inaccuracies, significantly impact accuracy.
- Individualized torso models are crucial for reliable pericardial potential estimation.
Purpose of the Study:
- To quantify the impact of electrode location and geometric errors on torso-surface models.
- To assess the accuracy of inverse solutions for pericardial potentials using individualized models.
- To evaluate the performance of regularization parameter estimation techniques.
Main Methods:
- Measured torso surface geometry and electrode locations in 11 adults using an Immersion Personal Digitizer.
- Estimated heart position, size, and orientation using ultrasonic images.
- Calculated body-surface ECGs from epicardial potentials using boundary-element methods and tested inverse solutions.
- Introduced noise and used fixed vs. individualized torso models to assess error.
Main Results:
- Individualized models with optimal regularization yielded a relative error of 0.44 +/- 0.03.
- Using a fixed torso model with calculated potentials increased relative error to 0.87 +/- 0.06.
- The CRESO technique failed in the fixed torso model, highlighting the need for personalization.
Conclusions:
- Fixed torso models are inadequate for accurate pericardial potential estimation.
- Individualized torso models significantly enhance the performance of inverse solution techniques.
- Accurate geometric and electrode localization data are essential for clinical applicability of inferred pericardial potentials.
