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Endometrial cancer in polyps associated with tamoxifen use
L M Ramondetta1, J B Sherwood, C J Dunton
1Department of Obstetrics and Gynecology and the Department of Pathology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Abstract:
We report 5 cases of carcinoma arising within tamoxifen-associated endometrial polyps. In 4 of 5 cases there were no other changes within the endometrium. Given these findings, the sonohysterographic differentiation between a polypoid structure and thickened endometrium does not eliminate the need for histologic sampling of the uterine cavity.
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