Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Is patient-controlled sedation good for elderly patients?]

T Kawabata1, J Tokumine, I Takara

  • 1Department of Anesthesiology, School of Medicine, University of the Ryukyus.

Masui. the Japanese Journal of Anesthesiology
|February 17, 1999
PubMed
Summary

Patient-controlled sedation (PCS) using propofol is safe and effective for elderly patients undergoing knee surgery with epidural anesthesia. This method provides sedation comparable to anesthesiologist-controlled sedation (ACS) with similar patient and surgeon satisfaction.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intratumoral microbiome is associated with the response to cancer immunotherapy in lung cancer patients with high PD-L1 expression.

Immuno-oncology technology·2025
Same author

Corrigendum to "Impact of BD BACTEC blood culture bottle shortage on performance metrics: An interrupted time-series analysis at a Japanese university-affiliated hospital" [J Infect Chemother (2025) 31(4) 102664].

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy·2025
Same author

Precise Spectroscopy of the 3n and 3p Systems via the ^{3}H(t, ^{3}He)3n and ^{3}He(^{3}He, t)3p Reactions at Intermediate Energies.

Physical review letters·2024
Same author

Validation of the ^{10}Be Ground-State Molecular Structure Using ^{10}Be(p,pα)^{6}He Triple Differential Reaction Cross-Section Measurements.

Physical review letters·2023
Same author

Mapping of a New Deformation Region around ^{62}Ti.

Physical review letters·2020
Same author

Damage accrual related to pregnancies before and after diagnosis of systemic lupus erythematosus: a cross-sectional and nested case-control analysis from a lupus registry.

Lupus·2020

Area of Science:

  • Anesthesiology
  • Geriatric Medicine
  • Surgical Sedation

Background:

  • Elderly patients undergoing surgery require careful sedation management.
  • Epidural anesthesia is commonly used for knee arthroplasty.
  • Patient-controlled sedation (PCS) offers potential advantages in sedation delivery.

Purpose of the Study:

  • To evaluate the safety and efficacy of intra-operative patient-controlled sedation (PCS) with propofol in elderly patients.
  • To compare propofol PCS with anesthesiologist-controlled sedation (ACS) during knee arthroplasty under epidural anesthesia.

Main Methods:

  • A randomized study comparing propofol PCS (n=6) and ACS (n=5) in elderly patients undergoing knee arthroplasty under epidural anesthesia.
  • Sedation levels, vital signs, blood gas analysis, and plasma propofol levels were monitored.

Related Experiment Videos

  • Patient and surgeon satisfaction surveys were conducted.
  • Main Results:

    • Patients in the PCS group received a lower mean dose of propofol (1.9 mg.kg-1) compared to the ACS group (2.9 mg.kg-1).
    • Procedure duration was similar in both groups (PCS: 147 min, ACS: 142 min).
    • Patient and surgeon satisfaction and complication incidence were similar between the PCS and ACS groups.

    Conclusions:

    • Intra-operative patient-controlled sedation (PCS) with propofol is a safe and effective sedation technique for elderly patients undergoing knee arthroplasty with epidural anesthesia.
    • PCS provides comparable sedation quality to anesthesiologist-controlled sedation (ACS) in this patient population.
    • PCS may allow for reduced propofol administration while maintaining satisfactory sedation and outcomes.