Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Hyperlipoproteinemias in psoriasis]

F Pfahl, J Rouffy, B Duperrat

Annales De Dermatologie Et De Syphiligraphie

|January 1, 1976

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML.

Oncogene·2016

Same author

A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function.

Cell death & disease·2014

Same author

SYK regulates mTOR signaling in AML.

Leukemia·2013

Same author

Sestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced death.

Cell death and differentiation·2012

Same author

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production.

Cell death and differentiation·2012

Same author

The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.

Leukemia·2011

Same journal

Clinical research on psoriasis therapy.

Annales de dermatologie et de syphiligraphie·2010

Same journal

Sulfamido-resistant gonococcal disease; Septicemia cured by penicillin.

Annales de dermatologie et de syphiligraphie·2010

Same journal

Pruritic dermatosis in glass wool.

Annales de dermatologie et de syphiligraphie·2010

Same journal

Ring of apparent preputial sclerosis in a circumcised ritual, in reality lymphangiomatous cystic dilation on scar.

Annales de dermatologie et de syphiligraphie·2010

Same journal

Association of lupus erythematosus and psoriasis in a tuberculous impregnated.

Annales de dermatologie et de syphiligraphie·2010

Same journal

Pruritus scrotal ferox with mutilating scratching lesions.

Annales de dermatologie et de syphiligraphie·2010

See all related articles

Psoriasis is strongly linked to type IV hyperlipoproteinaemia, a genetic condition causing high triglyceride levels. This finding suggests psoriasis may be a metabolic disease, potentially connected to glucose metabolism issues.

Area of Science:

Dermatology
Metabolic Medicine
Genetics

Context:

Psoriasis, a chronic inflammatory skin condition, is frequently associated with metabolic disturbances.
Type IV hyperlipoproteinaemia (endogenous hypertriglyceridaemia) is identified as a characteristic lipid profile in psoriatic patients.

Purpose:

To investigate the prevalence of type IV hyperlipoproteinaemia in patients with psoriasis.
To explore the potential link between psoriasis and metabolic diseases, specifically concerning glucose metabolism.

Summary:

Type IV hyperlipoproteinaemia was observed in 39% of psoriasis patients, significantly higher than in controls (18%).
The condition appears to be primarily genetic, with environmental factors playing a minimal role.
This association supports classifying psoriasis within metabolic diseases, given the high prevalence (80%) of pre-diabetic states in type IV hyperlipoproteinaemia.

Related Experiment Videos

Impact:

Highlights a significant metabolic comorbidity in psoriasis patients.
Suggests a need for screening psoriatic individuals for hypertriglyceridaemia and pre-diabetic conditions.
Advances understanding of psoriasis as a systemic metabolic disorder, not solely a skin condition.