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Epilepsy Research
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May 19, 2017
Anticonvulsant profile of the neuroactive steroid, SGE-516, in animal models
Rebecca S Hammond, Alison L Althaus, Michael A Ackley, et al.
The Journal of Biological Chemistry
|
June 27, 2019
Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABA<sub>A</sub> receptors
Manasa L Parakala, Yihui Zhang, Amit Modgil, et al.
The American Journal of Medicine
|
February 1, 1985
Multicenter collaborative evaluation of a standardized serum bactericidal test as a prognostic indicator in infective endocarditis
M P Weinstein, C W Stratton, A Ackley, et al.
Journal of Neuroscience Research
|
August 27, 2015
Rescue of deficient amygdala tonic γ-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel γ-aminobutyric acid type A receptor-positive allosteric modulator
Brandon S Martin, Gabriel Martinez-Botella, Carlos M Loya, et al.
Cellular and Molecular Life Sciences : CMLS
|
January 16, 2023
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions
Weiting Tang, Jacob T Beckley, Jin Zhang, et al.
British Journal of Pharmacology
|
September 12, 2023
Pharmacological characterization of SAGE-718, a novel positive allosteric modulator of N-methyl-d-aspartate receptors
Jacob T Beckley, Teresa K Aman, Michael A Ackley, et al.
Journal of Medicinal Chemistry
|
July 5, 2022
SAGE-718: A First-in-Class <i>N</i>-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment
Matthew D Hill, Maria-Jesus Blanco, Francesco G Salituro, et al.
Journal of Medicinal Chemistry
|
August 8, 2019
Neuroactive Steroid <i>N</i>-Methyl-d-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological Activity
Daniel S La, Francesco G Salituro, Gabriel Martinez Botella, et al.
Journal of Medicinal Chemistry
|
March 24, 2015
Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure-Activity Relationships of Heterocyclic Substitution at C-21
Gabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Journal of Medicinal Chemistry
|
July 29, 2017
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)<sub>A</sub> Receptor
Gabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Page
of 5
Search research articles
Search
Showing results (31-40 of 41) with videos related to
Sort By:
Page
of 5
Epilepsy Research
|
May 19, 2017
Anticonvulsant profile of the neuroactive steroid, SGE-516, in animal models
Rebecca S Hammond, Alison L Althaus, Michael A Ackley, et al.
The Journal of Biological Chemistry
|
June 27, 2019
Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABA<sub>A</sub> receptors
Manasa L Parakala, Yihui Zhang, Amit Modgil, et al.
The American Journal of Medicine
|
February 1, 1985
Multicenter collaborative evaluation of a standardized serum bactericidal test as a prognostic indicator in infective endocarditis
M P Weinstein, C W Stratton, A Ackley, et al.
Journal of Neuroscience Research
|
August 27, 2015
Rescue of deficient amygdala tonic γ-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel γ-aminobutyric acid type A receptor-positive allosteric modulator
Brandon S Martin, Gabriel Martinez-Botella, Carlos M Loya, et al.
Cellular and Molecular Life Sciences : CMLS
|
January 16, 2023
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions
Weiting Tang, Jacob T Beckley, Jin Zhang, et al.
British Journal of Pharmacology
|
September 12, 2023
Pharmacological characterization of SAGE-718, a novel positive allosteric modulator of N-methyl-d-aspartate receptors
Jacob T Beckley, Teresa K Aman, Michael A Ackley, et al.
Journal of Medicinal Chemistry
|
July 5, 2022
SAGE-718: A First-in-Class <i>N</i>-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment
Matthew D Hill, Maria-Jesus Blanco, Francesco G Salituro, et al.
Journal of Medicinal Chemistry
|
August 8, 2019
Neuroactive Steroid <i>N</i>-Methyl-d-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological Activity
Daniel S La, Francesco G Salituro, Gabriel Martinez Botella, et al.
Journal of Medicinal Chemistry
|
March 24, 2015
Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure-Activity Relationships of Heterocyclic Substitution at C-21
Gabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Journal of Medicinal Chemistry
|
July 29, 2017
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)<sub>A</sub> Receptor
Gabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Page
of 5