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Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 1, 1994
Metabolism of the proestrogenic pesticide methoxychlor by hepatic P450 monooxygenases in rats and humans. Dual pathways involving novel ortho ring-hydroxylation by CYP2BS S Dehal, D Kupfer
Biochemistry|February 25, 1997
Catalytic characteristics of CYP3A4: requirement for a phenolic function in ortho hydroxylation of estradiol and mono-O-demethylated methoxychlorD M Stresser, D Kupfer
Journal of Biochemical and Molecular Toxicology|September 15, 1998
Mechanism of induction of rat hepatic CYP2B and 3A by the pesticide methoxychlorH C Li, D Kupfer
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 12, 1998
Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylationD M Stresser, D Kupfer
The Journal of Biological Chemistry|February 25, 1985
Isolation by ion-exchange high performance liquid chromatography of rabbit liver cytochrome P-450 with regioselectivity for omega-hydroxylation of prostaglandinsK A Holm, D Kupfer
FEBS Letters|February 12, 1990
Inactivation of the uterine estrogen receptor binding of estradiol during P-450 catalyzed metabolism of chlorotrianisene (TACE). Speculation that TACE antiestrogenic activity involves covalent binding to the estrogen receptorD Kupfer, W H Bulger
Biochemical Pharmacology|August 26, 1998
Prosubstrates of CYP3A4, the major human hepatic cytochrome P450: transformation into substrates by other P450 isoformsD M Stresser, D Kupfer
Cancer Research|August 15, 1997
CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liverS S Dehal, D Kupfer
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 1, 1990
Role of P-450c in the formation of a reactive intermediate of chlorotrianisene (TACE) by hepatic microsomes from methylcholanthrene-treated ratsM J Juedes, D Kupfer
Neuroendocrinology|June 1, 1988
Hypothalamic action of delta-9-tetrahydrocannabinol to inhibit the release of prolactin and growth hormone in the ratV Rettori, T Wenger, G Snyder, et al.
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