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Showing results (31-40 of 42) with videos related to

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Journal of Medicinal Chemistry|January 18, 2018
Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral BioavailabilityJohn T Randolph, A Chris Krueger, Pamela L Donner, et al.
Journal of Medicinal Chemistry|October 27, 2006
Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetesZhonghua Pei, Xiaofeng Li, Thomas W von Geldern, et al.
Journal of Medicinal Chemistry|April 15, 2018
Highlights of the Structure-Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530)Rolf Wagner, John T Randolph, Sachin V Patel, et al.
Journal of Medicinal Chemistry|January 10, 2014
Discovery of ABT-267, a pan-genotypic inhibitor of HCV NS5ADavid A DeGoey, John T Randolph, Dachun Liu, et al.
Journal of Medicinal Chemistry|July 21, 2006
Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonistsZhili Xin, Michael D Serby, Hongyu Zhao, et al.
Journal of Medicinal Chemistry|February 20, 2009
Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazinesRolf Wagner, Daniel P Larson, David W A Beno, et al.
Journal of Medicinal Chemistry|June 9, 2006
Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitorsZhonghua Pei, Xiaofeng Li, Kenton Longenecker, et al.
Journal of Medicinal Chemistry|January 5, 2007
Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitorsJeffrey J Rohde, Marina A Pliushchev, Bryan K Sorensen, et al.
Journal of Medicinal Chemistry|January 11, 2008
Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitorGang Zhao, Andrew J Souers, Martin Voorbach, et al.
Bioorganic & Medicinal Chemistry Letters|December 26, 2006
Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylaminesAndrew J Souers, Rajesh R Iyengar, Andrew S Judd, et al.
Pageof 5

Showing results (31-40 of 42) with videos related to

Sort By:
Pageof 5
Journal of Medicinal Chemistry|January 18, 2018
Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral BioavailabilityJohn T Randolph, A Chris Krueger, Pamela L Donner, et al.
Journal of Medicinal Chemistry|October 27, 2006
Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetesZhonghua Pei, Xiaofeng Li, Thomas W von Geldern, et al.
Journal of Medicinal Chemistry|April 15, 2018
Highlights of the Structure-Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530)Rolf Wagner, John T Randolph, Sachin V Patel, et al.
Journal of Medicinal Chemistry|January 10, 2014
Discovery of ABT-267, a pan-genotypic inhibitor of HCV NS5ADavid A DeGoey, John T Randolph, Dachun Liu, et al.
Journal of Medicinal Chemistry|July 21, 2006
Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonistsZhili Xin, Michael D Serby, Hongyu Zhao, et al.
Journal of Medicinal Chemistry|February 20, 2009
Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazinesRolf Wagner, Daniel P Larson, David W A Beno, et al.
Journal of Medicinal Chemistry|June 9, 2006
Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitorsZhonghua Pei, Xiaofeng Li, Kenton Longenecker, et al.
Journal of Medicinal Chemistry|January 5, 2007
Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitorsJeffrey J Rohde, Marina A Pliushchev, Bryan K Sorensen, et al.
Journal of Medicinal Chemistry|January 11, 2008
Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitorGang Zhao, Andrew J Souers, Martin Voorbach, et al.
Bioorganic & Medicinal Chemistry Letters|December 26, 2006
Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylaminesAndrew J Souers, Rajesh R Iyengar, Andrew S Judd, et al.
Pageof 5