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Biochemistry|January 17, 1995
Modification of the electrostatic environment is tolerated in the oxyanion hole of the cysteine protease papainR Ménard, C Plouffe, P Laflamme, et al.
Protein Engineering|February 1, 1991
Removal of an inter-domain hydrogen bond through site-directed mutagenesis: role of serine 176 in the mechanism of papainR Ménard, C Plouffe, H E Khouri, et al.
The Journal of Biological Chemistry|July 14, 1995
Structural and functional roles of asparagine 175 in the cysteine protease papainT Vernet, D C Tessier, J Chatellier, et al.
The Journal of Biological Chemistry|September 25, 1990
Secretion of functional papain precursor from insect cells. Requirement for N-glycosylation of the pro-regionT Vernet, D C Tessier, C Richardson, et al.
The Journal of Biological Chemistry|March 5, 1993
Functional expression of human cathepsin S in Saccharomyces cerevisiae. Purification and characterization of the recombinant enzymeD Brömme, P R Bonneau, P Lachance, et al.
The Journal of Biological Chemistry|November 15, 1991
Processing of the papain precursor. Purification of the zymogen and characterization of its mechanism of processingT Vernet, H E Khouri, P Laflamme, et al.
FEBS Letters|July 10, 1998
An NMR-based identification of peptide fragments mimicking the interactions of the cathepsin B propeptideY Yu, W Vranken, N Goudreau, et al.
Biochemistry|September 17, 1991
Contribution of the glutamine 19 side chain to transition-state stabilization in the oxyanion hole of papainR Ménard, J Carrière, P Laflamme, et al.
Biochemistry|June 4, 1991
Importance of hydrogen-bonding interactions involving the side chain of Asp158 in the catalytic mechanism of papainR Ménard, H E Khouri, C Plouffe, et al.
Biochemistry|September 17, 1991
Engineering of papain: selective alteration of substrate specificity by site-directed mutagenesisH E Khouri, T Vernet, R Ménard, et al.
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