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Cell Reports. Medicine
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August 21, 2024
A pan-cancer screen identifies drug combination benefit in cancer cell lines at the individual and population level
Daniel J Vis, Patricia Jaaks, Nanne Aben, et al.
Nature Communications
|
May 11, 2026
Structural insights into cobalamin loading and reactivation of human methionine synthase
Douglas S M Ferreira, Katie McLennan, Calum Diamond, et al.
Journal of Medicinal Chemistry
|
February 8, 2024
Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase
Joshua J Maw, Jesse A Coker, Tarun Arya, et al.
Acta Crystallographica. Section D, Structural Biology
|
January 4, 2017
Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis
N Mills-Davies, D Butler, E Norton, et al.
Nucleic Acids Research
|
November 21, 2020
canSAR: update to the cancer translational research and drug discovery knowledgebase
Costas Mitsopoulos, Patrizio Di Micco, Eloy Villasclaras Fernandez, et al.
British Journal of Cancer
|
December 19, 2020
SLFN11 informs on standard of care and novel treatments in a wide range of cancer models
Claudia Winkler, Joshua Armenia, Gemma N Jones, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
April 25, 2012
An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases
D Bailey, E P Carpenter, A Coker, et al.
Oncogene
|
October 14, 2022
AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors
Shanade Dunn, Cath Eberlein, Jason Yu, et al.
Journal of Medicinal Chemistry
|
September 12, 2018
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS
Timothy R Hodges, Jason R Abbott, Andrew J Little, et al.
Nature Genetics
|
March 18, 2008
A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia
Ian M Morison, Elisabeth M Cramer Bordé, Emma J Cheesman, et al.
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Search research articles
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Showing results (171-180 of 187) with videos related to
Sort By:
Page
of 19
Cell Reports. Medicine
|
August 21, 2024
A pan-cancer screen identifies drug combination benefit in cancer cell lines at the individual and population level
Daniel J Vis, Patricia Jaaks, Nanne Aben, et al.
Nature Communications
|
May 11, 2026
Structural insights into cobalamin loading and reactivation of human methionine synthase
Douglas S M Ferreira, Katie McLennan, Calum Diamond, et al.
Journal of Medicinal Chemistry
|
February 8, 2024
Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase
Joshua J Maw, Jesse A Coker, Tarun Arya, et al.
Acta Crystallographica. Section D, Structural Biology
|
January 4, 2017
Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis
N Mills-Davies, D Butler, E Norton, et al.
Nucleic Acids Research
|
November 21, 2020
canSAR: update to the cancer translational research and drug discovery knowledgebase
Costas Mitsopoulos, Patrizio Di Micco, Eloy Villasclaras Fernandez, et al.
British Journal of Cancer
|
December 19, 2020
SLFN11 informs on standard of care and novel treatments in a wide range of cancer models
Claudia Winkler, Joshua Armenia, Gemma N Jones, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
April 25, 2012
An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases
D Bailey, E P Carpenter, A Coker, et al.
Oncogene
|
October 14, 2022
AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors
Shanade Dunn, Cath Eberlein, Jason Yu, et al.
Journal of Medicinal Chemistry
|
September 12, 2018
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS
Timothy R Hodges, Jason R Abbott, Andrew J Little, et al.
Nature Genetics
|
March 18, 2008
A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia
Ian M Morison, Elisabeth M Cramer Bordé, Emma J Cheesman, et al.
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of 19