Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

A D Hamilton

Showing results (51-60 of 85) with videos related to

Pageof 9
Sort By:
The Journal of Biological Chemistry|January 13, 1995
A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and Ras processingA Vogt, Y Qian, M A Blaskovich, et al.
Cancer Research|May 15, 1997
GGTI-298 induces G0-G1 block and apoptosis whereas FTI-277 causes G2-M enrichment in A549 cellsK Miquel, A Pradines, J Sun, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 21, 1995
Activated Drosophila Ras1 is selectively suppressed by isoprenyl transferase inhibitorsR C Kauffmann, Y Qian, A Vogt, et al.
Oncogene|October 7, 1997
Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell linesE C Lerner, T T Zhang, D B Knowles, et al.
Journal of Medicinal Chemistry|April 23, 1999
Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-IA Vasudevan, Y Qian, A Vogt, et al.
The Journal of Biological Chemistry|November 24, 1999
Integrin-dependent leukocyte adhesion involves geranylgeranylated protein(s)L Liu, P Moesner, N L Kovach, et al.
The Journal of Biological Chemistry|April 18, 1997
The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformationG J Clark, M S Kinch, K Rogers-Graham, et al.
Archives of Biochemistry and Biophysics|February 10, 2000
TGF-beta1 stimulation of fibronectin transcription in cultured human lung fibroblasts requires active geranylgeranyl transferase I, phosphatidylcholine-specific phospholipase C, protein kinase C-delta, and p38, but not erk1/erk2U Kucich, J C Rosenbloom, G Shen, et al.
Oncogene|December 15, 2000
Inhibition of farnesyltransferase increases TGFbeta type II receptor expression and enhances the responsiveness of human cancer cells to TGFbetaJ Adnane, F A Bizouarn, Z Chen, et al.
Molecular and Cellular Biology|December 14, 1999
The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosisK Jiang, D Coppola, N C Crespo, et al.
Pageof 9

Showing results (51-60 of 85) with videos related to

Sort By:
Pageof 9
The Journal of Biological Chemistry|January 13, 1995
A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and Ras processingA Vogt, Y Qian, M A Blaskovich, et al.
Cancer Research|May 15, 1997
GGTI-298 induces G0-G1 block and apoptosis whereas FTI-277 causes G2-M enrichment in A549 cellsK Miquel, A Pradines, J Sun, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 21, 1995
Activated Drosophila Ras1 is selectively suppressed by isoprenyl transferase inhibitorsR C Kauffmann, Y Qian, A Vogt, et al.
Oncogene|October 7, 1997
Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell linesE C Lerner, T T Zhang, D B Knowles, et al.
Journal of Medicinal Chemistry|April 23, 1999
Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-IA Vasudevan, Y Qian, A Vogt, et al.
The Journal of Biological Chemistry|November 24, 1999
Integrin-dependent leukocyte adhesion involves geranylgeranylated protein(s)L Liu, P Moesner, N L Kovach, et al.
The Journal of Biological Chemistry|April 18, 1997
The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformationG J Clark, M S Kinch, K Rogers-Graham, et al.
Archives of Biochemistry and Biophysics|February 10, 2000
TGF-beta1 stimulation of fibronectin transcription in cultured human lung fibroblasts requires active geranylgeranyl transferase I, phosphatidylcholine-specific phospholipase C, protein kinase C-delta, and p38, but not erk1/erk2U Kucich, J C Rosenbloom, G Shen, et al.
Oncogene|December 15, 2000
Inhibition of farnesyltransferase increases TGFbeta type II receptor expression and enhances the responsiveness of human cancer cells to TGFbetaJ Adnane, F A Bizouarn, Z Chen, et al.
Molecular and Cellular Biology|December 14, 1999
The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosisK Jiang, D Coppola, N C Crespo, et al.
Pageof 9