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The AAPS Journal
|
June 21, 2019
Guidance for Rifampin and Midazolam Dosing Protocols To Study Intestinal and Hepatic Cytochrome P450 (CYP) 3A4 Induction and De-induction
Asha J Kapetas, Michael J Sorich, A David Rodrigues, et al.
Molecular Pharmaceutics
|
June 16, 2018
Quantification of Hepatic Organic Anion Transport Proteins OAT2 and OAT7 in Human Liver Tissue and Primary Hepatocytes
Anna Vildhede, Emi Kimoto, A David Rodrigues, et al.
Expert Opinion on Drug Metabolism & Toxicology
|
October 6, 2007
Cytochrome P450 reaction-phenotyping: an industrial perspective
Hongjian Zhang, Carl D Davis, Michael W Sinz, et al.
Pharmaceutical Research
|
September 28, 2007
Projection of exposure and efficacious dose prior to first-in-human studies: how successful have we been?
Christine Huang, Ming Zheng, Zheng Yang, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
September 13, 2013
Assessment of vandetanib as an inhibitor of various human renal transporters: inhibition of multidrug and toxin extrusion as a possible mechanism leading to decreased cisplatin and creatinine clearance
Hong Shen, Zheng Yang, Weiping Zhao, et al.
Bioanalysis
|
April 19, 2023
LC-MS/MS method for the quantitation of OCT1 biomarker isobutyrylcarnitine in human plasma with clinical sample analysis
Amy Troop, Eugene Kadar, Emi Kimoto, et al.
Bioanalysis
|
February 20, 2024
Inception and development of a LC-MS/MS assay for the multiplexed quantitation of nine human drug transporter biomarkers
Eugene P Kadar, Christopher L Holliman, Manoli Vourvahis, et al.
Journal of Applied Toxicology : JAT
|
May 31, 2018
Species differences in bile acids II. Bile acid metabolism
Rhishikesh Thakare, Jawaher Abdullah Alamoudi, Nagsen Gautam, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
April 22, 2004
Cytochrome P450 2C8 (CYP2C8)-mediated hydroxylation of an endothelin ETA receptor antagonist in human liver microsomes
Bennett Ma, Raju Subramanian, Michael L Schrag, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
May 12, 2012
Impact of nonlinear midazolam pharmacokinetics on the magnitude of the midazolam-ketoconazole interaction in rats
Ragini Vuppugalla, Yueping Zhang, Shu Chang, et al.
Page
of 14
Search research articles
Search
Showing results (21-30 of 132) with videos related to
Sort By:
Page
of 14
The AAPS Journal
|
June 21, 2019
Guidance for Rifampin and Midazolam Dosing Protocols To Study Intestinal and Hepatic Cytochrome P450 (CYP) 3A4 Induction and De-induction
Asha J Kapetas, Michael J Sorich, A David Rodrigues, et al.
Molecular Pharmaceutics
|
June 16, 2018
Quantification of Hepatic Organic Anion Transport Proteins OAT2 and OAT7 in Human Liver Tissue and Primary Hepatocytes
Anna Vildhede, Emi Kimoto, A David Rodrigues, et al.
Expert Opinion on Drug Metabolism & Toxicology
|
October 6, 2007
Cytochrome P450 reaction-phenotyping: an industrial perspective
Hongjian Zhang, Carl D Davis, Michael W Sinz, et al.
Pharmaceutical Research
|
September 28, 2007
Projection of exposure and efficacious dose prior to first-in-human studies: how successful have we been?
Christine Huang, Ming Zheng, Zheng Yang, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
September 13, 2013
Assessment of vandetanib as an inhibitor of various human renal transporters: inhibition of multidrug and toxin extrusion as a possible mechanism leading to decreased cisplatin and creatinine clearance
Hong Shen, Zheng Yang, Weiping Zhao, et al.
Bioanalysis
|
April 19, 2023
LC-MS/MS method for the quantitation of OCT1 biomarker isobutyrylcarnitine in human plasma with clinical sample analysis
Amy Troop, Eugene Kadar, Emi Kimoto, et al.
Bioanalysis
|
February 20, 2024
Inception and development of a LC-MS/MS assay for the multiplexed quantitation of nine human drug transporter biomarkers
Eugene P Kadar, Christopher L Holliman, Manoli Vourvahis, et al.
Journal of Applied Toxicology : JAT
|
May 31, 2018
Species differences in bile acids II. Bile acid metabolism
Rhishikesh Thakare, Jawaher Abdullah Alamoudi, Nagsen Gautam, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
April 22, 2004
Cytochrome P450 2C8 (CYP2C8)-mediated hydroxylation of an endothelin ETA receptor antagonist in human liver microsomes
Bennett Ma, Raju Subramanian, Michael L Schrag, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
May 12, 2012
Impact of nonlinear midazolam pharmacokinetics on the magnitude of the midazolam-ketoconazole interaction in rats
Ragini Vuppugalla, Yueping Zhang, Shu Chang, et al.
Page
of 14