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Bioorganic & Medicinal Chemistry Letters
|
December 17, 2011
Identification of biaryl sulfone derivatives as antagonists of the histamine H₃ receptor: discovery of (R)-1-(2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916)
Graeme Semple, Vincent J Santora, Jeffrey M Smith, et al.
Journal of Medicinal Chemistry
|
September 3, 2009
Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity
Jonathan A Covel, Vincent J Santora, Jeffrey M Smith, et al.
Cell Chemical Biology
|
October 7, 2025
Discovery of a tau-aggregate clearing compound that covalently targets P4HB
Louis P Conway, Michelle A Estrada, Weichao Li, et al.
Environmental Science & Technology
|
December 22, 2025
Seasonality and Declining Intensity of Methane Emissions from the Permian and Nearby US Oil and Gas Basins
Daniel J Varon, Daniel J Jacob, Lucas A Estrada, et al.
Eukaryotic Cell
|
May 28, 2013
Frequency and genetic diversity of the MAT1 locus of Histoplasma capsulatum isolates in Mexico and Brazil
Gabriela Rodríguez-Arellanes, Carolina Nascimento de Sousa, Mauro de Medeiros-Muniz, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of a Highly Selective, Brain-Penetrant Aminopyrazole LRRK2 Inhibitor
Bryan K Chan, Anthony A Estrada, Huifen Chen, et al.
Science Translational Medicine
|
December 18, 2012
Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations
Zejuan Sheng, Shuo Zhang, Daisy Bustos, et al.
Journal of Medicinal Chemistry
|
March 21, 2024
Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases
Robert A Craig, Javier De Vicente, Anthony A Estrada, et al.
Journal of Medicinal Chemistry
|
December 22, 2007
Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity
Brian M Smith, Jeffrey M Smith, James H Tsai, et al.
Clinical and Translational Science
|
June 1, 2022
Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo-controlled, double-blind phase I/Ib studies in healthy subjects and patients
Maurits F J M Vissers, Jules A A C Heuberger, Geert Jan Groeneveld, et al.
Page
of 55
Search research articles
Search
Showing results (521-530 of 545) with videos related to
Sort By:
Page
of 55
Bioorganic & Medicinal Chemistry Letters
|
December 17, 2011
Identification of biaryl sulfone derivatives as antagonists of the histamine H₃ receptor: discovery of (R)-1-(2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916)
Graeme Semple, Vincent J Santora, Jeffrey M Smith, et al.
Journal of Medicinal Chemistry
|
September 3, 2009
Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity
Jonathan A Covel, Vincent J Santora, Jeffrey M Smith, et al.
Cell Chemical Biology
|
October 7, 2025
Discovery of a tau-aggregate clearing compound that covalently targets P4HB
Louis P Conway, Michelle A Estrada, Weichao Li, et al.
Environmental Science & Technology
|
December 22, 2025
Seasonality and Declining Intensity of Methane Emissions from the Permian and Nearby US Oil and Gas Basins
Daniel J Varon, Daniel J Jacob, Lucas A Estrada, et al.
Eukaryotic Cell
|
May 28, 2013
Frequency and genetic diversity of the MAT1 locus of Histoplasma capsulatum isolates in Mexico and Brazil
Gabriela Rodríguez-Arellanes, Carolina Nascimento de Sousa, Mauro de Medeiros-Muniz, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of a Highly Selective, Brain-Penetrant Aminopyrazole LRRK2 Inhibitor
Bryan K Chan, Anthony A Estrada, Huifen Chen, et al.
Science Translational Medicine
|
December 18, 2012
Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations
Zejuan Sheng, Shuo Zhang, Daisy Bustos, et al.
Journal of Medicinal Chemistry
|
March 21, 2024
Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases
Robert A Craig, Javier De Vicente, Anthony A Estrada, et al.
Journal of Medicinal Chemistry
|
December 22, 2007
Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity
Brian M Smith, Jeffrey M Smith, James H Tsai, et al.
Clinical and Translational Science
|
June 1, 2022
Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo-controlled, double-blind phase I/Ib studies in healthy subjects and patients
Maurits F J M Vissers, Jules A A C Heuberger, Geert Jan Groeneveld, et al.
Page
of 55