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A Engelhart

Showing results (41-50 of 51) with videos related to

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ACS Infectious Diseases|January 18, 2019
Investigation of ( S)-(-)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin SynthaseMatthew R Bockman, Curtis A Engelhart, Julia D Cramer, et al.
EMBO Molecular Medicine|December 7, 2020
Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosisBei Shi Lee, Kiel Hards, Curtis A Engelhart, et al.
ACS Infectious Diseases|February 27, 2025
Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of <i>Mycobacterium tuberculosis</i>Simon R Green, Justin R Harrison, Stephen Thompson, et al.
Journal of Medicinal Chemistry|November 10, 2023
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular ActivitySimon R Green, Caroline Wilson, Thomas C Eadsforth, et al.
Science (New York, N.Y.)|February 2, 2019
Opposing reactions in coenzyme A metabolism sensitize <i>Mycobacterium tuberculosis</i> to enzyme inhibitionElaine Ballinger, John Mosior, Travis Hartman, et al.
ACS Infectious Diseases|April 5, 2024
Inhibitors of the Thioesterase Activity of <i>Mycobacterium tuberculosis</i> Pks13 Discovered Using DNA-Encoded Chemical Library ScreeningInna V Krieger, Subbarao Yalamanchili, Paige Dickson, et al.
Journal of Medicinal Chemistry|January 4, 2021
Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action StudiesCandice Soares de Melo, Vinayak Singh, Alissa Myrick, et al.
Journal of Medicinal Chemistry|August 1, 2025
Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of TuberculosisSusan H Davis, Michael Mathieson, Kirsteen I Buchanan, et al.
Journal of Medicinal Chemistry|December 15, 2021
Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical TargetCaroline Wilson, Peter Ray, Fabio Zuccotto, et al.
ACS Omega|February 1, 2021
Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of <i>Mycobacterium tuberculosis</i> GrowthPeter C Ray, Margaret Huggett, Penelope A Turner, et al.
Pageof 6

Showing results (41-50 of 51) with videos related to

Sort By:
Pageof 6
ACS Infectious Diseases|January 18, 2019
Investigation of ( S)-(-)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin SynthaseMatthew R Bockman, Curtis A Engelhart, Julia D Cramer, et al.
EMBO Molecular Medicine|December 7, 2020
Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosisBei Shi Lee, Kiel Hards, Curtis A Engelhart, et al.
ACS Infectious Diseases|February 27, 2025
Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of <i>Mycobacterium tuberculosis</i>Simon R Green, Justin R Harrison, Stephen Thompson, et al.
Journal of Medicinal Chemistry|November 10, 2023
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular ActivitySimon R Green, Caroline Wilson, Thomas C Eadsforth, et al.
Science (New York, N.Y.)|February 2, 2019
Opposing reactions in coenzyme A metabolism sensitize <i>Mycobacterium tuberculosis</i> to enzyme inhibitionElaine Ballinger, John Mosior, Travis Hartman, et al.
ACS Infectious Diseases|April 5, 2024
Inhibitors of the Thioesterase Activity of <i>Mycobacterium tuberculosis</i> Pks13 Discovered Using DNA-Encoded Chemical Library ScreeningInna V Krieger, Subbarao Yalamanchili, Paige Dickson, et al.
Journal of Medicinal Chemistry|January 4, 2021
Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action StudiesCandice Soares de Melo, Vinayak Singh, Alissa Myrick, et al.
Journal of Medicinal Chemistry|August 1, 2025
Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of TuberculosisSusan H Davis, Michael Mathieson, Kirsteen I Buchanan, et al.
Journal of Medicinal Chemistry|December 15, 2021
Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical TargetCaroline Wilson, Peter Ray, Fabio Zuccotto, et al.
ACS Omega|February 1, 2021
Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of <i>Mycobacterium tuberculosis</i> GrowthPeter C Ray, Margaret Huggett, Penelope A Turner, et al.
Pageof 6